{"id":728,"date":"2022-03-22T17:48:23","date_gmt":"2022-03-22T17:48:23","guid":{"rendered":"https:\/\/purselab.sdsu.edu\/?p=728"},"modified":"2022-11-22T17:52:06","modified_gmt":"2022-11-22T17:52:06","slug":"new-manuscript-on-biorxiv","status":"publish","type":"post","link":"https:\/\/purselab.sdsu.edu\/new-manuscript-on-biorxiv\/","title":{"rendered":"New manuscript on bioRxiv"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"534\" src=\"http:\/\/purselab.sdsu.edu\/wp-content\/uploads\/2022\/11\/metabolic-labeling-1024x534.png\" alt=\"\" class=\"wp-image-727\" srcset=\"https:\/\/purselab.sdsu.edu\/wp-content\/uploads\/2022\/11\/metabolic-labeling-1024x534.png 1024w, https:\/\/purselab.sdsu.edu\/wp-content\/uploads\/2022\/11\/metabolic-labeling-300x156.png 300w, https:\/\/purselab.sdsu.edu\/wp-content\/uploads\/2022\/11\/metabolic-labeling-768x401.png 768w, https:\/\/purselab.sdsu.edu\/wp-content\/uploads\/2022\/11\/metabolic-labeling-1536x801.png 1536w, https:\/\/purselab.sdsu.edu\/wp-content\/uploads\/2022\/11\/metabolic-labeling-2048x1068.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Purse Lab Ph.D. student Ani Shalamberidze is working in collaboration with the <a rel=\"noreferrer noopener\" href=\"https:\/\/kleiner.princeton.edu\/\" target=\"_blank\">Kleiner Lab<\/a> at Princeton University on a new method for metabolic labeling and live-cell imaging of RNA. We have found that the right design of fluorescent ribonucleoside analogue combined with genetic up-regulation of the UCK2 enzyme of the pyrimidine salvage pathway enables fluorescent metabolic labeling to detect RNA synthesis, degradation, and trafficking in living cells. Check out the manuscript on bioRxiv: <a href=\"https:\/\/doi.org\/10.1101\/2022.03.22.485351\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1101\/2022.03.22.485351<\/a>. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Purse Lab Ph.D. student Ani Shalamberidze is working in collaboration with the Kleiner Lab at Princeton University on a new method for metabolic labeling and live-cell imaging of RNA. We have found that the right design of fluorescent ribonucleoside analogue &hellip; <a href=\"https:\/\/purselab.sdsu.edu\/new-manuscript-on-biorxiv\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-728","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/posts\/728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/comments?post=728"}],"version-history":[{"count":1,"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/posts\/728\/revisions"}],"predecessor-version":[{"id":729,"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/posts\/728\/revisions\/729"}],"wp:attachment":[{"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/media?parent=728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/categories?post=728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/purselab.sdsu.edu\/wp-json\/wp\/v2\/tags?post=728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}